Spontaneous pregnancy in a 45, X/46, X, r (X) Turner’s mosaic patient. Yuge A, Takai N, Nishida Y, Narahara H, Miyakawa I. Fertility and pregnancy outcome in Danish women with Turner syndrome. doi: 10.1111/j.īirkebaek NH, Crüger D, Hansen J, Nielsen J, Bruun-Petersen G. Genetic analysis of mosaicism in 53 women with Turner syndrome. Hanson L, Bryman I, Barrenäs ML, Janson PO, Wahlström J, Albertson-Wikland K, et al. Chromosomal mosaicism mitigates stigmata and cardiovascular risk factors in Turner syndrome. doi: 10.1007/s0043-x.Įl-Mansoury M, Barrenäs ML, Bryman I, Hanson C, Larsson C, Wilhelmsen L, et al. Turner syndrome revisited: review of new data supports the hypothesis that all viable 45, X cases are cryptic mosaics with a rescue cell line, implying an origin by mitotic loss. Mosaic TS cases should counseled about the low odds of pregnancy and high miscarriage rates. Age of menarche and age of marriage appear not to have any impact on the chance of conceiving. This syndrome affects approximately one in two thousand five hundred female births everywhere. Turner Syndrome was discovered in 1938 by Dr. Only a small proportion of the mosaic TS patients conceive in the first 2 years of the marriage. This syndrome is also referred to as Mosaic Turner Syndrome and Ullrich-Turner Syndrome and is a genetic condition that affects the sexual development in females. Mosaicism ratio did not have an effect on the time to the first pregnancy (p =. Fecundability analysis revealed that 5 % of the cases experienced first pregnancy within 6 months and 8 % within the first 2 years.
Implantation, clinical pregnancy and take home baby rates were detected as 3.7 %, 8.6 % and 5.7 %, respectively per IVF cycle as a result of 35 cycles.
Live birth and abortion rates were found as 32.7 % and 67.3 %, respectively in 52 pregnancies. Our aim is to evaluate reproductive and obstetric outcomes of natural conception and in-vitro fertilization (IVF) cycles in mosaic TS patients.Ī total of 22 mosaic TS cases (seventeen 45,X/46,XX and five 45,X/46,XX/47,XXX karyotypes) were evaluated. Chances of spontaneous pregnancy in TS are rare and the outcome of the pregnancies is known to be poor with an increased risk of miscarriage and stillbirths. Turner's syndrome (TS) is depicted as a total or partial absence of one X chromosome that results in ovarian dysgenesis.
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